Since 1972, Takeda has had two sites in Italy for producing plasma-derived drugs in Rieti and Pisa, supporting patients with rare and complex diseases. These sites focus on the production of therapies derived from immunoglobulins, albumin, and coagulation factors. As a partner of the National Health System, we transform plasma into life-saving drugs under the “National Self-Sufficiency of Blood and its Products” program. We provide high-quality drugs worldwide, with a strong presence in Europe, America, and Asia. Across Italy and the world, Takeda is recognized as a Top Employer by the Top Employers Institute based on our commitment to career development, inclusion, learning, sustainability, wellness, and, most importantly, our values. Join us to make a difference. **_ OBJECTIVES/PURPOSE:_**
- Manage the activities related to Process Improvement & Stewardship Team
- Lead process improvement initiatives, monitoring, and stewardship
- Provide technical support about manufacturing processes, investigations, optimization, yield improvement projects, cycle time reduction **_ ACCOUNTABILITIES:_**
- Manage and coordinate the Process Improvement team, ensuring that all team members are aligned with business objectives and operate efficiently
- Lead process improvement initiatives, monitoring, and stewardship
- Provide technical support about manufacturing processes, investigations, optimization, yield improvement projects, cycle time reduction, process robustness, Technology Transfer
- Oversee product and process investigations, product impact assessment, risk assessment
- Collaborate with all other departments to ensure an integrated and cohesive approach
- Ensure compliance with regulations and quality standards, keeping Quality by Design documents up to date
- Manage process validation strategy




- Support the preparation of regulatory submission / meetings
- Support regulatory inspections and defending technical decisions to regulatory agencies **_ CORE ELEMENTS RELATED TO THIS ROLE: _**
- Excellent leadership and team management skills
- Strong strategic orientation and analytical thinking ability
- Excellent communication, collaboration and influencing skills
- Experience in managing complex projects and implementing innovative technologies
- Ability to anticipate changes and solve complex problems
- Project management skills and results orientation
- Development of the team, providing strategic direction and support in complex scenarios
- Development of strategic plans for departmental growth and operational efficiency **_ DIMENSIONS AND ASPECTS - REQUIREMENTS:_** **Technical/Functional (Line) Expertise**
- Master or PhD degree in technical/scientific education, preferably pharmaceutical sciences, chemistry, biotechnology, bioinformatics or pharma - process engineering
- 5/7 previous experience in Leadership Role
- Previous experience in plasma fractionation processes (Ideal - Preferred) or in biotechnology field > knowledge of proteins > Knowledge of GMP/GDP (mandatory)
- Experience in Process Validation (preferred)
- Experienced in process optimization, capable of implementing strategies to enhance productivity
- Proficient in continuous improvement processes
- Proven experience in statistics,



data analysis or equivalent academic experience/course record
- Proven knowledge of six-sigma and DMAIC methodology
- Excellent knowledge of Italian and English, both written and spoken - Fluent level **Leadership**
- Focuses on the few priorities and delivers superior results
- Elevates the capabilities of the organization for now and the future
- Strategic enterprise thinking, finding innovative ways to serve patients build reputation and trust
- Good understanding of industry, scientific trends and market conditions to develop solutions enhancing compliance and quality of life for patients
- Organizational skills
- Good communication and presentation skills as well as influencing skills **Decision-making and Autonomy**
- Creating the environment that inspires and enables people
- Creates clarity, fostering alignment and accountability
- Is courageous in making decisions based on sound business judgment or appropriately escalate topics with high criticality **_ ADDITIONAL INFORMATION:_**
- Willingness to travel to various internal/external Takeda meetings and events **What Takeda can offer you**:
We want our employees to succeed in everything they do - at work, at home, and in the community. This is why we offer world-class benefits and access to resources that can support people. **Health and Finance**
- Health Care Assistance Insurance
- Employee Stock Purchase Plan
- Employee discount programs on commercial establishments, shops, medical services **Training and Development**
- Technical skill training and professional development
- Job Rotation programs for working in other departments
- Spontaneous employee groups for awareness on Diversity, Equity, and Inclusion issues and community engagement activ

📌 Head of Process Improvement & Stewardship - First Liters and Fractionation (Rieti)
🏢 Takeda Pharmaceutical
📍 Rieti