**APPLICATION CLOSING DATE: June 25th 2025** **Human Technopole (HT)**is an interdisciplinary life science research institute, created and supported by the Italian government, with the aim of developing innovative strategies to improve human health. HT has the mission of conducting cutting-edge research and to translate innovation into methods and tools available to the entire National scientific community. To this end, HT has opened National Facilities that provide world-class research infrastructure for Structural Biology, Light Imaging Microscopy, Genomics, Genome Engineering, and Data Handling and Analysis. The HCP infrastructural unit will work in synergy with the other National Facilities. **Key tasks and responsibilities**: - Design, develop, and optimize HCS and automation systems, including robotic workflows and integration of computational and biological inputs.
- Design, develop and validate biological assays in 2D and 3D format.
- Lead and manage a multidisciplinary team (3+ members).
- Build and expand internal HCS capabilities and infrastructure.
- Create and optimize cell-based and cell-free assays for screening campaigns.
- Manage projects across all stages—from assay development through screening and final data analysis.
- Maintain strong dialogue with users and stakeholders, ensuring project alignment with broader discovery goals.
- Establish and document SOPs, data communication protocols, and regulatory compliance if needed.
- Train, mentor, and support users and scientific staff in automated workflows and HCS technologies.
- Explore and implement new screening technologies and methodologies.. **Essential requirements**
- M.Sc. in biology or engineering.
- 5+ years’ experience (including postgraduate, postdoctoral or industry).
- Project management experience, especially in infrastructure setup and expansion.
- Experience in cell-based assay design, development and validation.
- Hands-on experience with:



- Liquid handling platforms and high content imaging systems.
- Large-scale screening campaigns.
- Cell culture (including complex systems like organoids, embryos, parasites).
- Fluency in English **Preferential requirements**
- Phd in biology or engineering is a plus
- Previous working experience in a core facility
- Programming knowledge in Python **Other key competencies**
- Leadership and mentoring capabilities.
- Strong technical expertise in facility operations and IT integration.
- Excellent organizational and strategic planning skills. **Application Instructions** To apply, please send the following: - a CV.
- a motivation letter in English relating your track record to the specifics of the call.
- names and contacts of 2 referees. **Why Human Technopole** HT seeks scientific excellence, we recruit the best scientific talents through international, open calls. Our working environment is international, friendly and inclusive. Our scientists work together across disciplines on research topics of biomedical relevance, leveraging synergies between their diverse skillsets and methodological approaches. We believe that highly diverse teams yield the best and most innovative results. We engage in outward-facing scientific activities aimed at benefiting the national and international research community. Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops. **Main benefits**
- Welfare plans.
- Meal delivery service.
- Work-life balance provisions.
- Italian language training for foreigners.
- Parental leave up to 1 year and other support for new parents.
- Flexible working hours.
- Support for relocation.
- Researchers coming to Italy for the first time, or returning after residing abroad, vantaggi from very attractive income tax benefits. Number of positions offered: 1 Contract offered: CCNL Chimico Farmaceutico, Fixed-term 3 years with possibility of renewal - Quadro Level
Tax benefits where applicable. The position is based in Milan.

📌 Unit Manager High Content Phenotyping (Hcp) (Milano)
🏢 Human Technopole
📍 Milano