Real World Evidence Lead Endo-Metabolic, Global Rare Diseases Department: GRD Global Medical Affairs Business Area: Mktg, Market Access, Bus.

Contract Type: Permanent Chiesi is an international research-focused biopharmaceutical group with 90 years’ experience, operating in more than 30 countries, with its Headquarter in Parma, Italy. This is what drives us as we research, develop, and market innovative drugs across our main therapeutic areas. At Chiesi we are thinking generations ahead, driving sustainable innovation with purpose.

As a Benefit Corporation and a certified B Corp, we have embedded sustainability in our bylaws and continuously measure our impact. We believe our differences make us stronger.

Chiesi Global Rare Diseases Chiesi Global

Rare Diseases is a Chiesi Group’s business unit established in February 2020 and focused on research, development and commercialization of treatments and patient support services for rare and ultra-rare disorders, many of whom have limited or no treatments available. This unit is based in Boston, Massachusetts, with a strong synergy with the headquarters in Parma. Rare unit has a focus on research and product development for lysosomal storage diseases, rare hematology, ophthalmology disorders and rare immunodeficiencies.

The unit is also a dedicated partner with global leaders in scientific research, patient advocacy and care. Reporting to the VP, RWE, the Real World Evidence Lead Endocrine-Metabolic (Endo-Met) is responsible for leading and executing the global RWE strategy and vision for the Endo-Met Portfolio within GRD. The role ensures the strategy, creation and updating of the integrated evidence generation plan (IEGP), in alignment with cross-functional partners to meet research and commercial objectives.

The role drives enterprise-level RWE impact, including building strategic data partnerships, advancing innovative methodologies, and influencing cross-functional decision‑making. Act as a change agent, effectively communicating the value of RWE and influencing adoption of new processes and approaches. Lead the global RWE strategy for the Endo-Met GRD portfolio, acting as the strategic RWE leader across development, regulatory, and commercialization phases, and ensuring its integration into regulatory, payer, and clinical decision-making across the Endo-Metabolic Portfolio including Myalepta® (metreleptin) in Lipodystrophy, Juxtapid® / Lojuxta® (lomitapide)



in Homozygous Familial Hypercholesterolemia (HoFH) and future pipeline or acquired assets.

Increase the integration of RWD sources to enhance evidence-based decision making through research programs, while providing medical leadership as appropriate on cross-functional teams supporting local and global needs in a prioritized manner. Continuously improve RWE capabilities, processes, and infrastructure to support global and local evidence generation for HIDO Build and scale RWE capabilities as a competitive advantage for GRD Lead change management to embed RWE into core organizational processes External Data & Partnership Strategy Lead identification, evaluation, and execution of external RWD partnerships and data acquisition strategies Oversee due diligence, contracting support, and governance of external data sources and collaborations Build long-term strategic relationships with academic institutions, data vendors, consortia, and healthcare systems Provide senior scientific leadership and deep technical expertise in observational research, epidemiology, and RWE methodologies Ensure adoption of innovative approaches, including AI/ML and advanced analytics, in RWE generation Act as the RWE subject matter expert within cross-functional teams (Medical, Clinical Development, Market Access, Regulatory) Influence asset strategies, development plans, and access strategies Represent Chiesi externally in scientific forums, consortia, and partnerships Maintain awareness of emerging trends, regulatory guidance, and methodological advances Leadership & Matrix Management Lead cross-functional and multidisciplinary teams in a matrix environment Manage consultants, mentor junior team members and as needed, direct reports over time Advanced degree (PhD, DrPH, MD, PharmD, MSc) in epidemiology, public health, health economics, or related field ~8+ years of experience in RWE, HEOR, epidemiology,



or observational research in pharma/biotech or related setting ~ Demonstrated success in leading RWE strategy at asset or portfolio level ~ Strong experience in real-world data sources (claims, EHR, registries, etc.) ~ Experience supporting regulatory and/or market access use of RWE ~ Deep expertise in epidemiology and RWE methodologies ~ Ability to translate evidence into business and clinical impact ~ Experience with advanced analytics, AI/ML, and innovative RWE approaches ~ Ability to shape data strategy and infrastructure decisions ~ Rare disease experience strongly preferred The final offer will reflect the candidate’s skills, experience,qualificationsand internal equity considerations. This role is eligible to participate in an annual bonus scheme, subject to company and individual performance.

In addition, we offer a comprehensive benefits package including , pension, private medical insurance, wellbeing programme, flexible benefits programme. Where the role is offered in a different country, the applicable salary, premio and benefits will be aligned to the relevant local market and internal frameworks. Full details of the applicable package will be provided at the appropriate stage of the recruitment process.

The role can be based in one of our affiliates in Europe, with an estimated 20% of travel requirement, including international travel Your future is our focus, and we are committed to nurturing your development in our dynamic, friendly environment with access to resources and training every step of the way. We provide top-class benefits, including comprehensive healthcare programs, work-life balance initiatives, and robust relocation support. Our salary package is competitive, comprising a basic salary, performance bonuses, and benefits benchmarked against the external market.

Additionally, we offer flexible working arrangements, remote work options, and tax assistance services for foreign colleagues, all designed to help you thrive. Chiesi is an equal opportunity employer committed to hiring a diverse workforce at all levels of our business. All qualified applicants receive consideration for employment based on attitude and merit, without regard to race, national origin, age, sex, religion, disability, sexual orientation, marital status, military status, gender identity or expression, or any other basis protected by applicable laws.

This policy applies to all aspects of employment, including hiring, transfer, promotion, compensation, eligibility for benefits, and termination. #

📌 Real World Evidence Lead Endo-Metabolic, Global Rare Diseases (Roma)
🏢 Biotecnologie - Farmacia - Chimica
📍 Roma