ppThe Laimburg Research Centre is the leading research institute for agriculture and food quality in South Tyrol (Italy).
We operate mainly in applied research with the aim of increasing the competitiveness and sustainability of South Tyrolean agriculture and of ensuring the quality of agricultural products.
/p pFor the research project BRIDGE "Exploring Bioactivity of Natural Compounds: From Encapsulation Strategies to Drug Discovery for Biomedical Targets", funded by Research Südtirol (call ****), CUP H33C , the working group "Laboratory of NMR Spectroscopy" at Laimburg Research Centre is looking for: /p pbResearcher - Code BR.26-NMR-***** /b /p pThe project aims to identify, characterize, and optimize bioactive compounds derived from apple and grape by-products, as well as elucidate their molecular mechanisms of action against protein aggregation associated with neurodegenerative diseases.
/p h3Your Responsibilities /h3 ul liExpression, purification, and characterization of recombinant amyloidogenic proteins /li liDevelopment and application of NMR methods to study protein aggregation and protein–ligand interactions /li liScreening of natural extracts, purified compounds, and encapsulated formulations as aggregation inhibitors using NMR spectroscopy and LC-MS /li liInvestigation of the molecular mechanisms underlying inhibition of amyloid formation /li liAnalysis of aggregation kinetics and biophysical data /li liPreparation of scientific reports, publications, and presentations /li liCollaboration with project partners in natural product chemistry, encapsulation technologies, and computational drug discovery /li /ul h3Your Profile /h3 ul liCompleted university studies of at least three years attested by a diploma in chemistry, biotechnology,



natural sciences or similar /li liGood knowledge of Italian or German (C1 level) language - to be evaluated during the interview /li liGood knowledge of English (B2 level) - to be evaluated during the interview /li /ul pFor this position, the following qualifications and competencies will be evaluated: /p ul liExperience in solution NMR spectroscopy (including experimental setup, pulse sequence implementation, and NMR data analysis) /li liExperience in data fitting, kinetic modelling, and the use of common computational tools for data analysis /li liKnowledge in expression, purification, and characterization of recombinant amyloidogenic proteins /li liScholarships and research grants (please specify in your CV) in fields related to the position's research topics /li liParticipation in national and international conferences (please specify in your CV if this involved a stay abroad) /li liPublication list with focus on organic chemistry, physical chemistry or chemistry of natural products /li liAvailability to start by November 1st, **** /li liGood organizational and communication skills /li liHigh motivation, ability to work independently, and strong team-working skills /li /ul h3What We Offer /h3 ul liAn innovative work environment in a cutting-edge research center /li liA supportive, appreciative team /li liFlexible working hours and the possibility for lavoro da remoto /li liSubsidized lunch /li liSupplementary health fund...and much more!
/li /ul pMore infos about our benefits on: /p pContract duration: until August 31st, **** - fulltime /p pApplications must arrive by and not later than August 31st, ************ a.m. /p pInterested?
/p pYou can find more information about the advertised position and how to apply in the application documents attached.
/p /p #J-*****-Ljbffr

📌 Researcher - Bridge Project (Bolzano)
🏢 Versuchszentrum Laimburg
📍 Bolzano