16 ago
|
Versuchszentrum Laimburg
|
Bolzano
16 ago
Versuchszentrum Laimburg
Bolzano
The Laimburg Research Centre is the leading research institute for agriculture and food quality in South Tyrol (Italy).
We operate mainly in applied research with the aim of increasing the competitiveness and sustainability of South Tyrolean agriculture and of ensuring the quality of agricultural products.
For the research project BRIDGE "Exploring Bioactivity of Natural Compounds: From Encapsulation Strategies to Drug Discovery for Biomedical Targets", funded by Research Südtirol (call ****), CUP H33C , the working group "Laboratory of NMR Spectroscopy" at Laimburg Research Centre is looking for:
Researcher - Code BR.26-NMR-*****
The project aims to identify, characterize, and optimize bioactive compounds derived from apple and grape by-products, as well as elucidate their molecular mechanisms of action against protein aggregation associated with neurodegenerative diseases.
Your Responsibilities
Expression, purification, and characterization of recombinant amyloidogenic proteins
Development and application of NMR methods to study protein aggregation and protein–ligand interactions
Screening of natural extracts, purified compounds, and encapsulated formulations as aggregation inhibitors using NMR spectroscopy and LC-MS
Investigation of the molecular mechanisms underlying inhibition of amyloid formation
Analysis of aggregation kinetics and biophysical data
Preparation of scientific reports, publications, and presentations
Collaboration with project partners in natural product chemistry, encapsulation technologies, and computational drug discovery
Your Profile
Completed university studies of at least three years attested by a diploma in chemistry, biotechnology,
natural sciences or similar
Good knowledge of Italian or German (C1 level) language - to be evaluated during the interview
Good knowledge of English (B2 level) - to be evaluated during the interview
For this position, the following qualifications and competencies will be evaluated:
Experience in solution NMR spectroscopy (including experimental setup, pulse sequence implementation, and NMR data analysis)
Experience in data fitting, kinetic modelling, and the use of common computational tools for data analysis
Knowledge in expression, purification, and characterization of recombinant amyloidogenic proteins
Scholarships and research grants (please specify in your CV) in fields related to the position's research topics
Participation in national and international conferences (please specify in your CV if this involved a stay abroad)
Publication list with focus on organic chemistry, physical chemistry or chemistry of natural products
Availability to start by November 1st, ****
Good organizational and communication skills
High motivation, ability to work independently, and strong team-working skills
What We Offer
An innovative work environment in a cutting-edge research center
A supportive, appreciative team
Flexible working hours and the possibility for lavoro da remoto
Subsidized lunch
Supplementary health fund...and much more!
More infos about our benefits on:
Contract duration: until August 31st, **** - fulltime
Applications must arrive by and not later than August 31st, ************ a.m.
Interested?
You can find more information about the advertised position and how to apply in the application documents attached.
#J-*****-Ljbffr
📌 Researcher - Bridge Project (Bolzano)
🏢 Versuchszentrum Laimburg
📍 Bolzano