This Full time on site position offers great opportunities for career growth. IRCCS San Raffaele Scientific Institute in Milan, Italy, is looking for a Lab Technician/Research Assistant to join the Process Development Lab (PDL), led by Marina Radrizzani at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) ( ), to work in projects focused on genetic engineering of T lymphocytes and hematopoietic stem cells (HSC). SR-Tiget was created in 1996 as a joint‑venture between Fondazione Telethon and Ospedale San Raffaele (OSR), with the mission to perform cutting edge research on gene and cell therapy and to translate its results into therapeutic advances for genetic diseases. The Institute is located within the OSR campus, which includes a large multi‑disciplinary research hospital, a biomedical research center, a university and also hosts several biotechnologies companies. Over the years, SR-Tiget has given a pioneering contribution to the gene and cell therapy field with relevant discoveries in vector design, gene transfer and gene editing strategies, stem cell biology,



identity and mechanism of action of regulatory cells in immune responses and innate immune cells in cancer. SR-Tiget has also established the resources and framework for translating these advances into novel experimental therapies and has implemented several successful gene therapy clinical trials, which have already treated >120 patients and led to the filing and approval of 2 novel advanced therapy medicines.

Sebbene l'esperienza competente e le qualifiche siano fondamentali per questo ruolo, si assicuri di verificare di possedere le soft skill preferenziali, se richieste, prima di candidarsi.
Main activities
- isolation, culture and genetic modification of T lymphocytes and HSC (lentiviral vector transduction, gene editing)
- process scale‑up and standardization
- cell‑based assays, molecular assays, flow cytometry analyses
- preparation of standard lab procedures and protocols
- gener

📌 LAB TECHNICIAN/RESEARCH ASSISTANT (Milano)
🏢 Ospedale San Raffaele
📍 Milano