Introduction:

Chaberton Professionals, the division of Chaberton Partners dedicated to the search and selection of Middle and Top Management profiles, is currently seeking a Global OPEX Manager on behalf of a multinational pharmaceutical group based in Florence. The company is a leading player in a highly regulated sector, with a strong focus on quality, innovation and operational efficiency. To strengthen industrial performance across its global network, it is looking for an experienced and proactive leader to drive Operational Excellence and continuous improvement initiatives.

The Company and the Role

A multinational pharmaceutical group with 9 finished product sites and 3 API sites, operating in a highly complex GMP environment. Within Global Manufacturing Support, the Operational Excellence & Cost pillar drives network-wide industrial performance and cost competitiveness through common standards, shared methodologies and a continuous improvement culture.

The company seeks a Global Manufacturing Operational Excellence Manager, reporting to the Global Operational Excellence Lead and working closely with production sites. The role supports network-level deployment of the Operational Excellence strategy, acts as the sites' methodological reference and leads complex, high-impact cross-site initiatives with local teams. It requires analytical skills, project leadership and a pragmatic focus on measurable productivity results. Day-to-day site operations remain with local structures.

Key Responsibilities:

- Productivity improvement: drive initiatives aimed at increasing labor productivity, OEE, manufacturing efficiency and capacity utilization
- Lean Manufacturing and problem solving: promote the adoption of Lean methodologies and structured problem-solving techniques across the network's sites
- Global Operational Excellence projects: lead cross-site projects involving multiple facilities,



partnering with the sites to identify and implement improvement opportunities
- Standards and validation: support the validation of manufacturing standards, cycle times and production capacity assumptions
- KPI and performance management: develop and maintain KPIs, reporting standards and common dashboards to support business decision-making
- Best practice sharing: foster the sharing of best practices and successful initiatives among the network's sites
- Cross-functional collaboration: work closely with Production, Engineering, Quality, Supply Chain, Finance and other corporate functions to ensure the successful execution of projects
- Capability building: contribute to the development of Operational Excellence skills and the widespread adoption of a continuous improvement culture throughout the network

Requirements:

- Education: a degree in a STEM field
- Experience: 7 to 10 years of experience in Manufacturing, Operational Excellence or Continuous Improvement, preferably in pharmaceutical contexts or regulated industries
- Technical skills: strong knowledge of Lean Manufacturing and Six Sigma methodologies; a solid understanding of pharmaceutical manufacturing processes and GMP requirements
- Analytical skills: experience in analyzing productivity, OEE, production capacity and manufacturing KPIs
- Project management: proven ability to manage cross-functional and international projects within dynamic environments
- Soft skills: a proactive, structured and results-oriented mindset, accompanied by excellent communication and stakeholder management skills across all organizational levels

Location: Florence, with international travel to network sites required (about 40–50% of the time).

Salary Package:

- CCNL for the Chemical and Pharmaceutical Industry
- Annual base salary between €60,000 and €65,000, including all applicable contractual and remuneration terms.

Retribuzione: €60.000,00 - €65.000,00 all'anno

Sede di lavoro: In presenza

📌 Global Opex Manager – Pharmaceutical Company (Firenze)
🏢 Chaberton Italia
📍 Firenze