Organisation/Company “G. d’Annunzio” University Chieti-Pescara Department DEPARTMENT OF PHARMACY Research Field Chemistry Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 16 Oct 2026 - 23:59 (Europe/Rome) Country Italy Type of Contract Temporary Job Status Full-time Is the job funded through the EU Research Framework Programme? Horizon Europe - MSCA Marie Curie Grant Agreement Number 101227308 Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Intrabrain is an innovative multinational, multisectorial, and multidisciplinary research and training programme that aims to create more efficacious vaccines using polymeric nanoparticles and self-assembled nanoplatforms in combination with modified oncolytic viruses to be used in glioblastoma. The DC will be based at the Department of Pharmacy at Università degli Studi “G. d’Annunzio” Chieti – Pescara (G. d’Annunzio University Chieti – Pescara, Italy – Ud’A). He/she will support the following INTRABRAIN activities:



development of nanoparticle formulations for virus protection and enhanced transfection, with a focus on improving antitumour efficacy in glioblastoma model, under the main supervision of Professor Piera Di Martino. The DC 4 will focus on (i) formulate PLGA nanoparticles loaded oncolytic virus; (ii) promote transfection of glioblastoma cells; (iii) demonstrate antitumour efficacy to glioblastoma cell lines. In detail, the candidate will (i) investigate the encapsulation efficacy of an oncolytic virus into PLGA nanoparticles produced under different techniques; (ii) characterise physicochemically the produced PLGA nanoparticles loaded oncolytic virus; (iii) demonstrate the transfection and antitumor efficacy in glioblastoma cell model.

The project offers the DC research and training excellence at the intersection of oncology and immunology. The partners of Intrabrain are leading research groups in molecular oncology, immunology,

📌 1 full-time Doctoral Candidate (Italia)
🏢 Universita Degli Studi G.D'Annunzio Chieti-Pescara
📍 Italia