Fondazione Telethon (FT) is a leading biomedical charity committed to advancing research into tangible therapeutic options for people living with rare genetic diseases. Through its affiliated research institutes – TIGEM (Naples) and SR-TIGET (Milan) – FT has established an internationally recognized track record in gene and cell therapy, genome engineering, RNA-based therapeutics, and translational medicine.

To further accelerate the development of next-generation therapeutic platforms, FT is establishing a cross-institute Artificial Intelligence Core for Protein Engineering, aimed at supporting the design, optimization, and translational development of therapeutic proteins, genome-editing enzymes, regulatory proteins, and other biologically relevant macromolecules. The Core will serve as a strategic computational platform integrating advances in machine learning, protein science, and functional genomics across TIGEM and SR-TIGET.

THE POSITION
FT is seeking an experienced and forward-thinking scientist to serve as Head of the AI Core for Protein Engineering,



leading an integrated initiative across TIGEM and SR-TIGET. The position offers a unique opportunity to shape a strategic enabling platform within the Fondazione Telethon R&D; ecosystem and contribute directly to the development of innovative therapeutic approaches.
The successful candidate will design, implement, and manage the AI Core, supporting translational research programs and enabling the application of state-of-the-art artificial intelligence methodologies to protein engineering challenges across the two Institutes.
The position will be based at TIGEM (Naples) and requires regular interactions and travel between the two sites.

Key Responsibilities
• Establish and lead the AI Core for Protein Engineering, ensuring alignment with the strategic priorities of the two Institutes
• Define and implement the Core’s scientific, methodological, and operational strategy, including workflows, data standards, benc

📌 Head of AI Core (Italia)
🏢 Fondazione Telethon
📍 Italia